Brindisi, represent one of the most safe port in the lower Adriatic Sea. The modern port was built at the end of a large funnel-shaped inlet that, according to many scientist, is the real mean of the name of the city.

The legend states that Falanto, the mythical founder of Taranto, driven by his own town, fled to Brindisi.

With the Roman occupation of 266 BC and the establishment of a Latin colony in 244 BC, Brindisi was transformed into the continent's main industrial, commercial and military port to the Easter Europe, and a strategic base for all the wars of the Roman Empire against Macedonia, Greece and Middle East regions.

With the fall of the Roman Empire (5th century), the Goths, Ostrogoths, Greeks and Byzantines. settled in the city.

At the time of the Crusades, Brindisi became the Gateway to the Middle East and to the Holy Land, than has been conquered by Emperor Frederick II Hohenstaufen that last the reconstruction.

Domination by domination, in Brindisi, the Bourbons conquered the town and in 1776 started works to the reopening of the channel entrance to the harbor. The works, designed and executed by the engineer Andrea Pia, caused an almost undergrounding of the port, which was little more then a swamp until its recovery done by Fernando II in 1869.

The port of Brindisi, following the construction of the Adriatic railway, was chosen as a terminal for goods shipment and passengers arriving on international trains. The first official trip of the Suitcase of India dated 25 October 1870.

In 1896, with the opening of the Suez Channel, the trades with the East increased rapidly.

During the First World War, the city became the scene of important naval operations and for this reason suffered numerous bombings obtaining, at the end of the war, the Cross of War Merit.